Antibodies Against Metapneumovirus Fusion (f) Protein and Uses Thereof

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Inventors

Andrew L. Feldhaus

Assignees

Icosavax, Inc.

Abstract

Provided are epitope-specific antigen-binding molecules specific to a human metapneumovirus (hMPV) Fusion (F) protein, in which the antigen-binding molecule comprises a variable domain that contacts the hMPV F protein. The antigen-binding molecule specific to an hMPV F protein comprises a heavy chain and a light chain. Further provided are methods for detecting antibodies specific to an hMPV F protein, a method comprising: a.) contacting a biological sample with an hMPV F protein; and b.) contacting an epitope-specific antigen-binding molecule with the hMPV F protein.

CovalX Technology Used

Epitope Mapping

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Categories : Patents, Epitope Mapping