Caninized Antibodies

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Inventors

Mohamad Morsey, Yuanzheng Zhang, Ian Tarpey

Assignees

Intervet Inc.

Abstract

The present invention discloses caninized antibodies with specific properties. The present invention also discloses caninized murine antibodies against canine PD-1 that have a high binding affinity for canine PD-1. The invention further discloses the use of the caninized antibodies of the present invention in the treatment of cancer in dogs.

CovalX Technology Used

Epitope Mapping
XL-MS

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Categories : Patents, Epitope Mapping