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EB1010, a putative Christensenellaceae-derived microbial peptide, exhibits anti-inflammatory activity and therapeutic potential in ulcerative colitis

Authors Maria L. Orsini Delgadoa, Camille Baudesson de Chanvillea, Hélène Pfistera, Laureen Bardouilleta, William Farina, Philippe Rinaudoa, Jessica ...

Discovery of Anti-SARS-CoV-2 XBB.1.5 and JN.1 Variant-Specific Monoclonal Single-Domain Antibodies from a Synthetic Library

Authors Isamu Tsuji1, Kumiko Okada2, Benjamin Kroppen3, Tetsufumi Katta2, Kaori Yamamura2, Takeshi Nishihama2, Ayako Miura1, Hansjörg Götzke3, Eric ...

Human Capital Is the Most Valuable

Authors Renato Zenobi Organizations ETH Zürich, Zürich, Switzerland Abstract In early October 2025, I attended the farewell party for ...

Discovery and Characterization of Two anti-PD-1 Antibodies with a Unique Binding Mechanism to human PD-1

Authors Keyla María Gómez Castellanoa,b, Alejandra Montes Lunaa,b, Gregorio de Jesús Carballo Uicaba,b, Frida ...

FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Designed for Optimal CD137 Engagement Resulting in Potent Conditional T-Cell Activity

Authors Matthew A. Lakins1, Christel Séguy Veyssier2, Jose Munoz-Olaya1, Emma Goodman1, Robert Hughes1, James J Day1, Quincy Kaka1, Jennifer ...

Integrating Multiple MS Techniques for in-Depth Antibody Glycosylation Analysis: Revealing Glycosylation-Dependent Structural and Functional Properties

Authors Yuye Zhou1,2, Sophia Schedin Weiss3, Congrui Tan1, Philipp Bittner1, Julian A. Harrison4, Lars Tjernberg3, Asa Emmer2, Renato Zenobi1 Organizations ...

Dendrimer Conjugates with PD-L1-Binding Peptides Enhance In Vivo Antitumor Immune Response

Authors DaWon Kim1, Jin Woong Lee1, Piper A. Rawding1, Mari Iida2, Carter Kim1, Kourtney L. Kostecki2, Michael J. Poellmann1, Bridget ...

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