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Dendrimer Conjugates with PD-L1-Binding Peptides Enhance In Vivo Antitumor Immune Response

Authors DaWon Kim1, Jin Woong Lee1, Piper A. Rawding1, Mari Iida2, Carter Kim1, Kourtney L. Kostecki2, Michael J. Poellmann1, Bridget ...

The Tetravalent, Bispecific Properties of FS118, an Anti-LAG-3/PD-L1 Antibody, Mediate LAG-3 Shedding from CD4+ and CD8+ Tumor-Infiltrating Lymphocytes

Authors Claire S. Reader1, Wenjia Liao2, Beatrice J. Potter-Landua1, Christel Séguy Veyssier1, Claire J. Seal1, Neil Brewis2, Michelle Morrow1 ...

Formation of Amyloid-Like Conformational States of β-Structured Membrane Proteins on the Example of OMPF Porin from the Yersinia pseudotuberculosis Outer Membrane

Authors Olga D. Novikova1, Tatyana V. Rybinskaya1, Elena A. Zelepuga1, Vladimir N. Uversky2, Nataliya Yu1. Kim, Ekaterina A. Chingizova1, Ekaterina ...

Trogocytosis Targeting Chimeras (TrogoTACs) for Targeted Protein Transfer

Authors Nicholas A. Till1,2, Muthukumar Ramanathan2,3, Kang Yong Loh1,2, and Carolyn R. Bertozzi1,2,4 Organizations Department of Chemistry, Stanford University, Stanford, ...

Rapid Profiling of the Glycosylation Effects on the Binding of SARS-CoV-2 Spike Protein to Angiotensin-Converting Enzyme 2 Using MALDI-MS with High Mass Detection

Authors Yuye Zhou, Congrui Tan, Renato Zenobi Organizations Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), ...

Co-opting the E3 Ligase KLHDC2 for Targeted Protein Degradation by Small Molecules

Authors Christopher M. Hickey, Katherine M. Digianantonio, Kurt Zimmermann, Alicia Harbin, Connor Quinn, Avani Patel, Peter Gareiss, Amanda Chapman, Bernadette ...

Epitope Mapping of Monoclonal Antibodies: A Comprehensive Comparison of Different Technologies

Authors Xibei Danga, Lars Guelenb, David Lutje Hulsikb, Grigori Ermakova, Edward J. Hsieha, Joost Kreijtzb, Judith Stammen-Vogelzangsb, Imke Lodewijksb, Astrid ...

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