Patents and Publications

08Dec 2011

The Structural Basis For Increased Toxicity of Pathological AB42:AB40 Ratios in Alzheimer’s Disease

Authors Kris Pauwels1, Thomas L. Williams2, Kyle L. Morris2, Wim Jonckheere3,4, Annelies Vandersteen3,4, Geoff Kelly1, Joost Schymkowitz3,4, Frederic Rousseau3,4, Annalisa ...
01Dec 2011

Compelling Advantages of Negative Ion Mode Detection in High-Mass MALDI-MS for Homomeric Protein Complexes

Authors Stefanie Mädler1, Konstantin Barylyuk1, Elisabetta Boeri Erba1, Robert J. Nieckarz1, and Renato Zenobi1 Organizations Department of Chemistry and ...
22Nov 2011

Detection of Nucleic Acid-Nuclear Hormone Receptor complexes with mass spectrometry

Authors Claudia Bich1, Cédric Bovet1, Natacha Rochel2, Carole Peluso-Iltis2, Andreas Panagiotidis3, Alexis Nazabal4, Dino Moras2, and Renato Zenobi1 Organizations ...
20Oct 2011

A Specific Protein Disorder Catalyser of HIV-1 Nef

Authors Adrien Lugari1, Sebastian Breuer2, Thibault Coursindel3, Sandrine Opi4,5,6, Audrey Restouin4,5,6, Xiaoli Shi1,7, Alexis Nazabal8, Bruce E. Torbett2, Jean Martinez3, ...
03Oct 2011

Monitoring Ligand Modulation of Protein-Protein Interactions by Chemical Cross-Linking And High-Mass MALDI Mass Spectrometry

Authors Natalia Gasilova1 and Alexis Nazabal1 Organizations Chemical Proteomics: Methods and Protocols, Methods in Molecular Biology, vol. 803 Abstract Analyzing the ...
17May 2011

Direct Mass Spectrometric Analysis of Aggregates of Therapeutic Protein

Inventors Alexis Nazabal and Ryan Jay Wenzel Assignees Covalx AG Abstract The invention relates to a method of using high-mass ...
23Dec 2010

Does Chemical Cross-Linking with NHS Esters Reflect the Chemical Equilibrium of Protein-Protein Noncovalent Interactions in Solution?

Authors Stefanie Mädler1, Markus Seitz2, John Robinson2, and Renato Zenobi1 Organizations Department of Chemistry and Applied Biosciences, ETH Zurich, ...
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