Patents and Publications

16Apr 2018

Assessment of Pharmacology and Toxicology of Anti-CTLA-4 Antibody (ADU-1604) in Non-Human Primates and Evaluation of Local Anti-CTLA-4 Application

Authors Maaike Hendriks1, Joost Kreijtz1, Paul Vink1, David Lutje Hulsik1, Imke Lodewijks1, Astrid Bertens1, Jos van de Crommert1, Maurice Habraken1, ...
22Mar 2018

TREM-1 Multimerization Is Essential for Its Activation on Monocytes and Neutrophils

Authors Kevin Carrasco1,2, Amir Boufenzer1, Lucie Jolly1,2, Helene Le Cordier3, Guanbo Wang4, Albert JR Heck4, Adelheid Cerwenka5, Emilie Vinolo1, Alexis ...
21Mar 2018

Binding Specificities of Nanobody•Membrane Protein Complexes Obtained from Chemical Cross-Linking and High-Mass MALDI Mass Spectrometry

Authors Martin Köhler1, Christoph Neff1, Camilo Perez2, Cyrill Brunner1, Els Pardon3, Jan Steyaert3, Gisbert Schneider1, Kaspar P. Locher2, Renato ...
20Mar 2018

Imaging Activated T Cells Predicts Response to Cancer Vaccines

Authors Israt S. Alam1,2, Aaron T. Mayer1,2,3, Idit Sagiv-Barfi4, Kezheng Wang1,5, Ophir Vermesh1,2, Debra K. Czerwinski4, Emily M. Johnson1,2,6, Michelle ...
18Feb 2018

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

Authors Chia-Wei Li1, Seung-Oe Lim1,12, Ezra M. Chung11, Yong-Soo Kim11, Andrew H. Park11, Jun Yao1, Jong-Ho Cha1,4, Weiya Xia1, Li-Chuan ...
12Nov 2017

XL-MS Direct Comparison with X-Ray Crystallography Epitope Binding Sites Case Study

Authors Lilit Simonyan1, Mamadou Sy1, Ryan Wenzel2, David Lutje-Hulsik3, Hans van Eenennaam3, Alexis Nazabal4 Organizations CovalX Analytics SA, 146 rue Lé...
12Sep 2017

High-Mass MALDI-MS Analysis for the Investigation of Protein Encapsulation within an Engineered Capsid Forming Protein

Authors Katharina Root1, Raphael Frey1, Donald Hilvert1, Renato Zenobi1 Organizations Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 ...
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