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High-Mass Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Absolute Quantitation of Noncovalent Protein–Protein Binding Interactions

Authors Na Wu1, Lingyi Jiao1, Matthias Bütikofer1, Zhihui Zeng2,3, Renato Zenobi1 Organizations Department of Chemistry and Applied Biosciences, ETH ...

Determining the Stoichiometry of a Protein–Polymer Conjugate Using Multisignal Sedimentation Velocity Analytical Ultracentrifugation

Authors Susan M. Clardy1, David H. Lee1, Peter Schuck2 Organizations Mersana Therapeutics Inc., Cambridge, Massachusetts 02139, United States National Institutes of ...

Heme-Induced Ferroptosis Promotes Human Lumbar Disc Degeneration Analyzed by MALDI-TOF MS

Authors Liang Shan1, Ximing Xu2, Jing Zhang3, Peng Cai4, Han Gao1, Yingjie Lu5, Jiangang Shi2, Yinlong Guo3, Yue Su5 Organizations ...

Humanized, Mouse Or Chimeric Anti-CD47 Monoclonal Antibodies

Inventors Nicola Beltraminelli, Marie CHÂLONS-COTTAVOZ, Stéphanie FALLOT, Pierre Garrone, Mehdi Lahmar, Klaus Schwamborn Assignees Forty Seven Inc Abstract ...

Hallmarks of Alpha and Betacoronavirus Non-Structural Protein 7+8 Complexes

Authors Boris Krichel1, Ganesh Bylapudi2, Christina Schmidt3, Clement Blanchet4, Robin Schubert3, Lea Brings3, Martin Koehler5, Renato Zenobi5, Dmitri Svergun4, Kristina ...

An IgG-Based Bispecific Antibody for Improved Dual Targeting in PSMA-Positive Cancer

Authors Latifa Zekri1,2,3, Fabian Vogt1, Lukas Osburg1, Stefanie Müller2,3, Joseph Kauer1,2,3, Timo Manz1, Martin Pflügler1,2,3, Andreas Maurer4, Jonas ...

The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism

Authors Thomas C. Buckles1, Yohei Ohashi2, Shirley Tremel2, Stephen H. McLaughlin2, Els Pardon3,4, Jan Steyaert3,4, Moshe T.Gordon1, Roger L....

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