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Two Patient Studies of a Companion Diagnostic Immuno-Positron Emission Tomography (PET) Tracer for Measuring Human CA6 Expression in Cancer for Antibody Drug Conjugate (ADC) Therapy

Authors Arutselvan Natarajan1, Shyam M. Srinivas1, Carmen Azevedo1, Lacey Greene1, Anne-Laure Bauchet2, Erwan Jouannot2, Anne-Sophie Lacoste-Bourgeacq2, Isabelle Guizon2, Patrick Cohen2, ...

In Silico and in Vitro Investigations on the Protein–Protein Interactions of Glutathione S-transferases with Mitogen-activated Protein Kinase 8 and Apoptosis Signal-regulating Kinase 1

Authors Chakradhara Rao S. Uppugunduri1,2, Jayaraman Muthukumaran3,4, Shannon Robin2, Teresa Santos- Silva3 and Marc Ansari1,2 Organizations Onco-Haematology Unit, Department of ...

Combination Therapy For The Treatment of Cancer

Inventors Nancy Lewis Assignees NOVARTIS AG (Basel, CH) Abstract Dosing regimens for the administration of complexes comprising IL-15/IL-15Ra ...

Anti-Complement Factor C1Q Antibodies and Uses Thereof

Inventors Arnon Rosenthal and Michael Leviten Assignees ANNEXON, INC. (South San Francisco, CA, US) Abstract The present invention provides anti-C1...

ANTIBODY ADJUVANT CONJUGATES

Inventors Michael Nathaniel Alonso, Edgar George Engleman, Shelley Erin Ackerman, Justin Kenkel, Arthur Lee, David Y Jackson. Assignees The Board ...

Aβ(1-42) Tetramer and Octamer Structures Reveal Edge Conductivity Pores as a Mechanism for Membrane Damage

Authors Sonia Ciudad1,9, Eduard Puig1, Thomas Botzanowski2, Moeen Meigooni3, Andres S. Arango3, Jimmy Do3, Maxim Mayzel4, Mariam Bayoumi5, Stéphane ...

CD9P-1-Targeting Antibody and Use Thereof

Inventors Sylvie Colin Assignees Gene Signal International SA (Lausanne, CH) Abstract The present disclosure relates to an isolated protein that ...

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