Anti-Tigit Antigen-Binding Proteins And Methods Of Use Thereof



Philipp Steiner, Nels P. NIELSON, Daniel Hicklin, Cynthia Seidel-Dugan, William Winston, Heather BRODKIN, Jose-Andres Salmeron-Garcia, Christopher James NIRSCHL


  1. Potenza Therapeutics, Inc., 1030 Massachusetts Avenue, Suite 210, Cambridge, MA 02139 (US)


Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.

CovalX Technology Used

Epitope Mapping

Patent Number

WO 2018/183889 Al

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Categories : Patents, Epitope Mapping