Patents and Publications

01Aug 2024

Pharmaceutical Composition for Treating Brain Diseases Comprising Antibody Specifically Binding to ASM Protein as Active Ingredient

Inventors Seung Beom Hong, Jae Sung BAE, Hee Kyung Jin Assignees ISU ABXIS Co Ltd, Industry Academic Cooperation Foundation of ...
04Jul 2024

Formation of Amyloid-Like Conformational States of β-Structured Membrane Proteins on the Example of OMPF Porin from the Yersinia pseudotuberculosis Outer Membrane

Authors Olga D. Novikova1, Tatyana V. Rybinskaya1, Elena A. Zelepuga1, Vladimir N. Uversky2, Nataliya Yu1. Kim, Ekaterina A. Chingizova1, Ekaterina ...
03Jun 2024

Trogocytosis Targeting Chimeras (TrogoTACs) for Targeted Protein Transfer

Authors Nicholas A. Till1,2, Muthukumar Ramanathan2,3, Kang Yong Loh1,2, and Carolyn R. Bertozzi1,2,4 Organizations Department of Chemistry, Stanford University, Stanford, ...
30Jan 2024

ANTI-PD-L1 ANTIBODIES AND USES THEREOF

Inventors Horacio G. Nastri, Needham, MA Assignees Merck Patent GmbH, Darmstadt (DE) Abstract The present application relates to anti-PD-L1 antibodies ...
27Jan 2024

Rapid Profiling of the Glycosylation Effects on the Binding of SARS-CoV-2 Spike Protein to Angiotensin-Converting Enzyme 2 Using MALDI-MS with High Mass Detection

Authors Yuye Zhou, Congrui Tan, Renato Zenobi  Organizations Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), ...
04Jan 2024

Co-opting the E3 Ligase KLHDC2 for Targeted Protein Degradation by Small Molecules

Authors Christopher M. Hickey, Katherine M. Digianantonio, Kurt Zimmermann, Alicia Harbin, Connor Quinn, Avani Patel, Peter Gareiss, Amanda Chapman, Bernadette ...
27Nov 2023

Epitope Mapping of Monoclonal Antibodies: A Comprehensive Comparison of Different Technologies

Authors Xibei Danga, Lars Guelenb, David Lutje Hulsikb, Grigori Ermakova, Edward J. Hsieha, Joost Kreijtzb, Judith Stammen-Vogelzangsb, Imke Lodewijksb, Astrid ...
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