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Co-opting the E3 Ligase KLHDC2 for Targeted Protein Degradation by Small Molecules

Authors Christopher M. Hickey, Katherine M. Digianantonio, Kurt Zimmermann, Alicia Harbin, Connor Quinn, Avani Patel, Peter Gareiss, Amanda Chapman, Bernadette ...

Epitope Mapping of Monoclonal Antibodies: A Comprehensive Comparison of Different Technologies

Authors Xibei Danga, Lars Guelenb, David Lutje Hulsikb, Grigori Ermakova, Edward J. Hsieha, Joost Kreijtzb, Judith Stammen-Vogelzangsb, Imke Lodewijksb, Astrid ...

Anti-BTN3A Antibodies For Use In Methods Of Treating Gastro-Intestinal Inflammatory Disorders

Inventors Sophie AGAUGUE, Paul Frohna Assignees Imcheck Therapeutics Abstract It is disclosed BTN3A inhibitory antibodies for use in treating ...

Transferrin Receptor (tfr)-selective Binding Peptides Capable of Crossing the Blood Brain Barrier and Methods of Use Thereof

Inventors Pawel Stocki, Krzysztof Bartlomiej Wicher, Jaroslaw Michal Szary, Julia Lynn Rutkowski Assignees Ossianix Inc Abstract The present invention relates ...

Methods For Treating Anemia of Kidney Disease

Inventors Brian Macdonald, John QUISEL, Will SAVAGE, Hua Yang, Jonathan Yu, Min Wu, Maria BECONI, Jennifer M. Perez, Bernhard Mueller, ...

Mertk Peptides and Uses Thereof

Inventors Masoud Tavazoie, Isabel Kurth, Shugaku Takeda, David M. Darst Assignees MERTK (mer proto-oncogene tyrosine-protein kinase) Abstract The present disclosure ...

Discovery and Optimization of Neutralizing SARS-CoV-2 Antibodies Using ALTHEA Gold Plus Libraries™

Authors Omar U. Guzmán-Bringas1,2, Keyla M. Gómez-Castellano1,2, Edith González-González1,2, Juana Salinas-Trujano1,2, Said Vázquez-Leyva1,2, Luis Vallejo-Castillo1,2, ...

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