Caninized Rat Antibodies To Canine Interleukin-31 Receptor Alpha

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Inventors

Mohamad Morsey, Yuanzheng Zhang, Anasuya SAHA

Abstract

The present invention provides caninized rat antibodies to canine IL-31 receptor alpha that have a high binding affinity for canine IL-31 receptor alpha, and that can block the binding of canine IL-31 to canine IL-31 receptor alpha. The present invention further provides the use of the antibodies for the treatment of atopic dermatitis in dogs.

CovalX Technology Used

Epitope Mapping
XL-MS

Source

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Categories : Patents, Epitope Mapping