In complement to the crosslinking-MS technology for conformational epitope mapping, CovalX is now offering another method based on mass spectrometry: Hydrogen/Deuterium exchange (HDX) coupled with mass spectrometry (HDXMS). This method is allowing characterization of conformational epitopes with a resolution of 5-6 amino acids. To perform these analysis, CovalX is using a robotic sample handling system in combination with nLC-Orbitrap MS/MS analysis. This instrumentation gives repeatability, resolution and robustness to the analysis.
This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.