CovalX Crosslinking Kits Brochure
This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Crosslinking Kits
Talk to Our Scientists
CovalX Crosslinking Kits
Because of the tendency of these complexes to dissociate during analysis, the analysis of protein complexes by mass spectrometry is typically labor intensive. CovalX has developed a method for the easy and fast analysis of protein complexes using High-Mass MALDI mass spectrometry coupled with chemical crosslinking. The first step of the analysis is to stabilize the noncovalent complexes of interest using the CovalX dedicated cross-linking reagents and protocols. After stabilization, the sample is ready for direct analysis by High-Mass ToF mass spectrometry.
To effectively analyze intact protein complexes by High-Mass MALDI ToF mass spectrometry, it is crucial to stabilize specifically the complexes with highly efficient cross-linking reagents. CovalX has developed dedicated reagent and buffers to prepare non-covalent protein complexes for High-Mass MALDI analysis. To increase cross-linking efficiency, CovalX’s reagents contain cocktails of cross-linkers with different spacer lengths able to covalently bind specific protein complexes with the highest efficiency. The specificity of CovalX cross-linking reagents allows you to covalently stabilize linked protein complexes even in contaminated or unpurified samples.
MALDI MS Analysis Kits and Reagents for Protein Interactions:
| MALDI MS Analysis Kits and Reagents | Mass Range | Part No. |
|---|---|---|
| K50 MALDI MS Analysis Kit | 0-50 kDa | W2010k50 |
| K100 MALDI MS Analysis Kit | 20-100 kDa | W2010k100 |
| K200 MALDI MS Analysis Kit | 100-1000 kDa | W2010k200 |
| R50 Stabilizer Reagent | 0-50 kDa | W2010R50 |
| R100 Stabilizer Reagent | 20-100 kDa | W2010R100 |
| R200 Stabilizer Reagent | 100-1000 kDa | W2010R200 |
To learn more or order our crosslinking kits
Contact Us, Email us at info@covalx.com, call us at +1(617) 297 2263