Canine Antibodies With Modified Ch2-Ch3 Sequences



Mohamad Morsey, Yuanzheng Zhang, Ian Tarpey


  1. Intervet International BV


The present invention discloses caninized antibodies with specific properties. The present invention also discloses caninized murine antibodies againstcanine PD-1 that have a high binding affinity for canine PD-1. The invention further discloses the use of the caninized antibodies of the present invention in the treatment of cancer in dogs.

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Categories : Patents