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Anti-CD19 CAR T Cells That Secrete a Biparatopic Anti-CLEC12A Bridging Protein Have Potent Activity Against Highly Aggressive Acute Myeloid Leukemia In Vitro and In Vivo

Authors Paul D. Rennert, Fay J. Dufort, Lihe Su, Tom Sanford, Alyssa Birt, Lan Wu, Roy R. Lobb, Christine Ambrose ...

Stable Gold-Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens

Authors Kevin R. Trabbic1, Kristopher A. Kleski1, and Joseph J. Barchi Jr1 Organizations Chemical Biology Laboratory, Center for Cancer Research, ...

High-Mass MALDI-MS Unravels Ligand-Mediated G Protein–Coupling Selectivity to GPCRs

Authors Na Wu1, Agnieszka M. Olechwier2,3, Cyrill Brunner1, Patricia C. Edwards4, Ching-Ju Tsai2, Christopher G. Tate4, Gebhard F. X. Schertler2, ...

High-Mass Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Absolute Quantitation of Noncovalent Protein–Protein Binding Interactions

Authors Na Wu1, Lingyi Jiao1, Matthias Bütikofer1, Zhihui Zeng2,3, Renato Zenobi1 Organizations Department of Chemistry and Applied Biosciences, ETH ...

Determining the Stoichiometry of a Protein–Polymer Conjugate Using Multisignal Sedimentation Velocity Analytical Ultracentrifugation

Authors Susan M. Clardy1, David H. Lee1, Peter Schuck2 Organizations Mersana Therapeutics Inc., Cambridge, Massachusetts 02139, United States National Institutes of ...

Heme-Induced Ferroptosis Promotes Human Lumbar Disc Degeneration Analyzed by MALDI-TOF MS

Authors Liang Shan1, Ximing Xu2, Jing Zhang3, Peng Cai4, Han Gao1, Yingjie Lu5, Jiangang Shi2, Yinlong Guo3, Yue Su5 Organizations ...

Hallmarks of Alpha and Betacoronavirus Non-Structural Protein 7+8 Complexes

Authors Boris Krichel1, Ganesh Bylapudi2, Christina Schmidt3, Clement Blanchet4, Robin Schubert3, Lea Brings3, Martin Koehler5, Renato Zenobi5, Dmitri Svergun4, Kristina ...

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