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An IgG-Based Bispecific Antibody for Improved Dual Targeting in PSMA-Positive Cancer

Authors Latifa Zekri1,2,3, Fabian Vogt1, Lukas Osburg1, Stefanie Müller2,3, Joseph Kauer1,2,3, Timo Manz1, Martin Pflügler1,2,3, Andreas Maurer4, Jonas ...

The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism

Authors Thomas C. Buckles1, Yohei Ohashi2, Shirley Tremel2, Stephen H. McLaughlin2, Els Pardon3,4, Jan Steyaert3,4, Moshe T.Gordon1, Roger L....

Two Patient Studies of a Companion Diagnostic Immuno-Positron Emission Tomography (PET) Tracer for Measuring Human CA6 Expression in Cancer for Antibody Drug Conjugate (ADC) Therapy

Authors Arutselvan Natarajan1, Shyam M. Srinivas1, Carmen Azevedo1, Lacey Greene1, Anne-Laure Bauchet2, Erwan Jouannot2, Anne-Sophie Lacoste-Bourgeacq2, Isabelle Guizon2, Patrick Cohen2, ...

In Silico and in Vitro Investigations on the Protein–Protein Interactions of Glutathione S-transferases with Mitogen-activated Protein Kinase 8 and Apoptosis Signal-regulating Kinase 1

Authors Chakradhara Rao S. Uppugunduri1,2, Jayaraman Muthukumaran3,4, Shannon Robin2, Teresa Santos- Silva3 and Marc Ansari1,2 Organizations Onco-Haematology Unit, Department of ...

Aβ(1-42) Tetramer and Octamer Structures Reveal Edge Conductivity Pores as a Mechanism for Membrane Damage

Authors Sonia Ciudad1,9, Eduard Puig1, Thomas Botzanowski2, Moeen Meigooni3, Andres S. Arango3, Jimmy Do3, Maxim Mayzel4, Mariam Bayoumi5, Stéphane ...

Analysis of High Molecular Weight Polyrotaxanes by MALDI-TOFMS using 3-aminoquinoline-based Ionic Liquid Matrix

Authors Yuzo Yamazaki1, Shuuichi Nakaya1, Kozo Ito2, Kazuaki Kato2 Organizations Global Application Development Center, Analytical & Measuring Instruments Division, Shimadzu ...

Temporal Activation of WNT/β-Catenin Signaling is Sufficient to Inhibit SOX10 Expression and Block Melanoma Growth

Authors Rexhep Uka1, Christian Britschgi1, Anja Krättli1, Claudia Matter1, Daniela Mihic2, Michal J. Okoniewski3, Marco Gualandi1, Roger Stupp1, Paolo ...

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